Bacterial Gene Regulation Pathway with Red Luciferase Reporter System #2294682 (License: Personal Use)

The diagram depicts a genetically engineered bacterial cell containing a regulatory cascade: pTetR represses Ho1 and PcyA expression until induced; Ho1 converts heme to biliverdin, which binds PCB to form the chromophore for red luciferase (Cph1). Upon red light illumination, Cph1 emits luminescence, while parallel pathways involving OmpR and EnvZ regulate membrane protein expression (e.g., OmpC) and antibiotic resistance (AmpRes). The system integrates optogenetics, metabolic engineering, and transcriptional control.

Used in synthetic biology and microbiology educational or research web pages to explain optogenetic reporter systems, metabolic pathway engineering, or bacterial biosensor design; targets students, researchers, and biotech developers seeking mechanistic clarity.