T Helper Cell Differentiation and Macrophage Infection Dynamics - Immunology Model #1617146 (License: Personal Use)

This scientific diagram models the immune response involving CD4+ T helper (Th) cell differentiation from Th0 precursors into Th1 (pro-inflammatory) and Th2 (anti-inflammatory/humoral) subsets, governed by parameters like θ₁δₘ and θ₂δᴮ. It integrates macrophage dynamics-including phagocytosis of bacilli, infection of macrophages, bursting of infected cells, and death/supply rates-with kinetic constants (e.g., kᵢ, kₗ, k_b, μ terms) to represent a quantitative systems immunology framework.

Used in academic publications, immunology textbooks, or online educational platforms to explain adaptive immunity mechanisms, host-pathogen interactions (e.g., tuberculosis), and mathematical modeling of immune responses; targets researchers, students, and clinicians seeking mechanistic insight.