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p53 Protein Interaction Network Diagram - DNA Repair & Cancer Pathways #1951000 (License: Personal Use)

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Protein-protein interaction network centered on p53, showing key DNA repair and tumor suppressor proteins.

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This scientific diagram illustrates a protein-protein interaction (PPI) network with tumor suppressor p53 as the central hub, surrounded by DNA damage response proteins (e.g., ATM/ATR substrates), ubiquitin ligases (e.g., MDM2, HUWE1), and repair complexes (e.g., RAD50-RAD23A-MSH2). Key nodes include SMC3, ML8, and PCNA, reflecting roles in chromatin remodeling, replication stress, and mismatch repair. Lines denote experimentally validated physical or functional interactions.
Used in molecular oncology, bioinformatics, and cancer research webpages to explain p53’s regulatory role; ideal for educational content, review articles, or interactive pathway tools targeting researchers and students.
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Related Cliparts: Visualize the complex protein interaction network centered on tumor suppressor p53, including DNA repair proteins like RAD51, BRCA1-associated factors, and MDM2 regulators.

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