Historical Smallpox Infection Photo: Medical Documentation from Early 20th Century #3674905 (License: Personal Use)

This early 20th-century clinical photograph captures two young boys side-by-side, illustrating the variable presentation of smallpox infection. The boy on the left suffers from confluent smallpox, with dense, raised pustules covering his face and torso, while the boy on the right displays only sparse, discrete lesions-possibly indicating variola minor or early-stage disease. The image was likely taken in a hospital or quarantine facility, with natural light from a window illuminating their upper bodies.

This image is commonly used in medical history resources, epidemiology studies, and public health campaigns to illustrate the impact of smallpox before eradication. It serves educational purposes for students, historians, and clinicians studying infectious disease manifestations and vaccine efficacy.