BNP-PEG40K Peptide Conjugate Structure | Bioconjugation Chemistry #1207130 (License: Personal Use)

This schematic illustrates a bioconjugate where brain natriuretic peptide (BNP) is linked at the ε-amino group of lysine-14 to a polyethylene glycol (PEG40K) moiety via a spacer containing a maleimide-functionalized thiol-reactive end. The conjugate includes a hexamethylene linker and amide bonds, designed to enhance pharmacokinetics and reduce immunogenicity. Stereochemistry is indicated at chiral centers using bold/dashed wedges.

Used in pharmaceutical R&D pages, scientific publications, or biotech product documentation to illustrate advanced peptide-polymer conjugates for cardiovascular therapeutics; matches user intent for understanding molecular design of PEGylated peptides.