Neurodegenerative Disease Mechanisms - Cellular Pathways Explained #16884 (License: Personal Use)

The image illustrates three primary pathological categories-protein granule foci (e.g., TDP-43, FUS), protein environmental foci (e.g., Aβ plaques, α-synuclein Lewy bodies), and strategic degeneration patterns (e.g., frontotemporal, corticobasal, midbrain). Each pathway shows how misfolded proteins trigger neuroinflammation, synaptic dysfunction, and selective neuronal death, with brain cross-sections below indicating regional vulnerability.

Used in neuroscience education, medical journals, or patient-facing resources to explain disease etiology; targets researchers, clinicians, and informed patients seeking mechanistic understanding of neurodegeneration.