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Brain-Gut Axis and Stress Response Pathway Explained #3779192 (License: Personal Use)

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Diagram illustrating the brain-gut axis and stress response pathway involving HPA axis, vagus nerve, immune system, and gut microbiota.

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The image maps the neurobiological cascade initiated by stress, starting with prefrontal cortex (PFC), hippocampus (HIPP), and amygdala (AMG) inputs to the hypothalamus (HYP), which releases CRF to stimulate ACTH from the anterior pituitary and cortisol from adrenal glands. Concurrently, the vagus nerve modulates gut activity and immune responses, while enteric microbiota influence CRF release, GI motility, and mast cell activation-highlighting bidirectional communication in the brain-gut-immune network.
Used in medical, neuroscience, or functional medicine articles explaining psychoneuroimmunology, IBS, anxiety-gut links, or stress-related disorders; targets clinicians, researchers, and informed patients seeking mechanistic understanding.
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Related Cliparts: Discover how stress triggers the HPA axis, vagus nerve, immune activation, and gut dysbiosis-key mechanisms in the brain-gut axis. Learn implications for health.

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